In English? Utterly, at least without an extensive author's note, and it would be an impediment to my reading, as it would be more or less me having to translate from a foreign language into English as I read.

If it were acknolwedged to be a non-English construction that is somehow necessary to the setting (I've got a set of pronouns in signifier that are created because dragons are hermaphroditic) for a secondary-world or SFnal setting, I might bother to stick with it long enough for that eye-tripping "this is not English wth does it mean" period to wear off. I might not. It'd depend.